I’m out of the drug trial, but here are some details
Dec 3rd, 2005 Posted in celiac disease | 3 comments »After taking my medical history at the Screening Visit, I was excluded from this drug trial, but I did learn quite a few details about the trial.
The drug being tested is the one I suspected, a zonulin antagonist developed by Alba Therapeutics and currently known as AT-1001. It is hoped that eventually, if the drug makes it to market, people with Celiac disease would be able to take this drug 3 times a day and resume eating gluten at will.
The trial is a double blind placebo controlled study. Participants and those directly caring for them will not know if they are getting a placebo or the drug.
All participants will be fed a snack or a meal duriung a 3-day hospitalization that will contain gluten. Nobody being tested or directly involved with participants will know which snack or meal contains the gluten.
2 out of each 3 participants will be getting the trial drug, 1 in 3 will get a placebo.
It is reasonable to expect that those getting the placebo who then eat gluten will react in some way, at least some of them.
Medical care will be immediately available for any patients reacting to the gluten.
If this test goes as hoped, it is estimated that it will still be 6 to 8 years until this drug could become generally available as a prescription drug.
I'll be home in another 24 hours, until then I'll not have Internet access.
